Biostatistical methods
Course information
Lecture in master program, Fall term 2009
Instructors: Prof. Dr. Leonhard Held and Dr. Kaspar Rufibach, University of Zurich, Institute for Social and Preventive Medicine, Biostatistics Unit
Time and venue
- Exercises: Friday, 10-11
- Lecture: Friday, 11-13
Institute for Social and Preventive Medicine, Biostatistics unit, Hirschengraben 84, Room F05.
Details of the exam
- Date and time: January 15, 10-12 (duration 2 hours)
- Venue: Irchel, lecture hall Y03G91
- Details: open book (all materials are allowed), no own laptops and pocket calculators. Pocket calculators will be provided.
Program
The lecture discusses two important fields of biostatistics: Epidemiological and clinical studies.The first part, taught by Prof. Held, deals with the analysis of case-control and cohort studies.
The most relevant measures of effect (odds and rate ratios) are introduced, and methods for adjusting
for confounders (Mantel-Haenszel, regression) are thoroughly discussed.
In the second part, taught by Dr. Rufibach, methods from clinical trials such as
planning, conduct and analysis of randomized trials, sample size computations, equivalence and
sequential tests are discussed.